If music played over your Airport Express cuts out on a regular basis, if your new Nintendo Wii can't reliably connect to the Internet, if your VPN keeps dropping its connection: change the channel.
802.11b/g wireless networks can operate on any of a dozen slightly different frequencies, and most wireless access points are configured to use channel 1 by default. If you have many wireless access points in your neighborhood, or other wireless devices using similar frequencies (like cordless phones) or other kinds of interference, changing the channel of your access point can make a difference as great as night and day. Try channel 6 or channel 11.
The best part is most client devices don't need to be re-configured to use the new channel, they will simply discover the change the next time they try to connect.